Direct Inhibition of Mitochondrial Respiratory Chain Complex III by Cell-permeable Ceramide
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چکیده
منابع مشابه
Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide.
Ceramide is a lipid second messenger that mediates the effects of tumor necrosis factor alpha and other agents on cell growth and differentiation. Ceramide is believed to act via activation of protein phosphatase, proline-directed protein kinase, or protein kinase C. Tumor necrosis factor alpha-induced common pathway of apoptosis is associated with an early impairment of mitochondria. Herein, w...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1997
ISSN: 0021-9258
DOI: 10.1074/jbc.272.39.24154